Hermite–Poulain theorem
For a polynomial $f(x) = \sum_k a_k x^k$, write $f(D) = \sum_k a_k D^k$, where $D = d/dx$. If $f$ and $p$ are real-rooted, then $f(D)\,p$ is zero or real-rooted.
References
The theorem goes back to Hermite and Poulain; see the Hermite–Poulain theorem on symmetricfunctions.com for further references.